Gene involved in colorectal cancer also causes breast cancer

Rare mutations in the NTHL1 gene, previously associated with colorectal cancer, also cause breast cancer and other types of cancer. Researchers from Radboud university medical center, Leiden University Medical Center and the Princess Máxima Center in the Netherlands report this new multi-tumor syndrome, in collaboration with international colleagues, in Cancer Cell. Nicoline Hoogerbrugge, professor of Hereditary Cancer at Radboud university […]

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Multifocal breast cancer: Definition, staging, prognosis, and treatment

There are many types of breast cancer. The type and characteristics, including the number of tumors and where they are, can affect a person’s treatment and long-term outlook. This article covers information about multifocal breast cancer, including how doctors diagnose and treat the condition, its prognosis, and recurrence rates. What is multifocal breast cancer? A person who has received a […]

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Women with persistent hot flushes are more at risk of breast cancer

Women who suffer persistent hot flushes during the menopause are more likely to develop breast cancer Study of 25,000 post-menopausal women who did not have HRT Fluctuating oestrogen levels are thought to be behind hot flushes High oestrogen exposure has been linked to a greater risk of breast cancer   e-mail View comments Women who suffer persistent hot flushes during the menopause […]

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Medication beliefs affect uptake of preventive Tx for breast cancer

(HealthDay)—Beliefs about medication are associated with uptake of tamoxifen as a preventive therapy among women at increased risk for breast cancer, according to a study published online Dec. 2 in Clinical Breast Cancer. Rachael Jane Thorneloe, Ph.D., from the University of Leeds in the United Kingdom, and colleagues surveyed 732 women attending an appointment to discuss breast cancer risk. Just […]

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Black women have worse breast cancer outcomes despite receiving similar treatment as white women

Even with equivalent treatments in women with hormone receptor-positive, HER2-negative breast cancer, black women had significantly higher breast cancer recurrence and increased overall mortality compared to white women in a large phase III clinical trial, TAILORx, according to data presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8. “Our findings are consistent with prior studies indicating that […]

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Delaying adjuvant chemo associated with worse outcomes for patients with triple-negative breast cancer

Patients with triple-negative breast cancer who delayed starting adjuvant chemotherapy for more than 30 days after surgery were at significantly higher risk for disease recurrence and death compared with those who started the treatment in the first 30 days after surgery, according to a retrospective study presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8. “For this […]

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The ‘wrong’ connective tissue cells signal worse prognosis for breast cancer patients

In certain forms of cancer, connective tissue forms around and within the tumour. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumour in different ways. Now, a research team at Lund University in Sweden has identified three different types of connective tissue cells. In […]

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Rare variants associated with interval breast cancers

(HealthDay)—Though common breast cancer variants indicate increased breast cancer risk, certain rare variants are associated with an increased risk for interval breast cancers and death, according to a study published in the Nov. 1 issue of Cancer Research. Jingmei Li, Ph.D., from the Genome Institute of Singapore, and colleagues assessed whether the genetic risk stratification of breast cancer by rare […]

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