How decisions unfold in a zebrafish brain

Some things we do appear almost automatic, like opening the fridge when feeling hungry or flipping on the air conditioning when the temperature rises. Although such decisions don’t seem to take much thought, they are in fact generated by millions of neurons and numerous interactions among several brain regions—a dynamic system so complex that scientists aren’t able to observe it […]

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Brain tumor organoids may be key to time-sensitive treatments for glioblastomas

Lab-grown brain organoids developed from a patient’s own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. A new study in Cell from researchers at Penn Medicine showed how glioblastoma organoids could serve as effective models to rapidly test personalized treatment strategies. Glioblastoma multiforme (GBM) remains the most difficult […]

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Early detection of brain degeneration on the horizon with innovative sensor

Neurodegenerative diseases such as Alzheimer’s and Parkinson’s can be devastating to patients and their families. These diseases are difficult to diagnose before symptoms show, meaning it’s often already too late to reverse the damage to the central nervous system. Early detection is key for management of symptoms and attempts to stall progression of the disease, but current knowledge is limited […]

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Woman saved by colleagues after having brain haemorrhage at work Christmas party

Trudi Kemp was enjoying a chat with a colleague at a work Christmas party, a glass of wine in one hand and a plate of nibbles in the other. But within a few minutes, she had collapsed on the floor and was fighting for her life. At the time, Trudi, from Wimbledon, south west London, was working as executive director […]

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Scientists eager to explain brain rhythm boost’s broad impact in Alzheimer’s models

The sweeping extent to which increasing 40Hz “gamma” rhythm power in the brain can affect the pathology and symptoms of Alzheimer’s disease in mouse models has been surprising, even to the MIT neuroscientists who’ve pioneered the idea. So surprising, in fact, they can’t yet explain why it happens. In three papers, including two this year in Cell and Neuron, they’ve […]

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Dementia study reveals how proteins interact to stop brain signals

Fresh insights into damaging proteins that build up in the brains of people with Alzheimer’s disease could aid the quest for treatments. A study in mice reveals how the two proteins work together to disrupt communication between brain cells. Scientists observed how proteins—called amyloid beta and tau—team up to hamper key genes responsible for brain messaging. By changing how genes […]

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Women who take the Pill have a smaller hypothalamus in the brain

Women who take the Pill each day have an ‘essential’ brain region which is 6% SMALLER, scientists discover The hypothalamus is crucial for the normal production of hormones The small region plays a role in mood, appetite, sex drive and sleep This is the first time changes to its size have been found in women using the Pill   Early research […]

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Deep neural networks uncover what the brain likes to see

Opening the eyes immediately provides a visual perception of the world—and it seems so easy. But the process that starts with photons hitting the retina and ends with ‘seeing’ is far from simple. The brain’s fundamental task in ‘seeing’ is to reconstruct relevant information about the world from the light that hits the eyes. Because this process is rather complex, […]

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Mum who thought she just had 'baby brain' actually had a brain tumour

A new mum who put her headaches and tiredness down to ‘baby brain’ was devastated to discover she actually had an incurable brain tumour. Claire Curtis, 30, had been experiencing headaches and feeling tired for months before her diagnosis, but just put it down to the stress of being a new mum. Doctors prescribed her medication for migraines, but when […]

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