Ragweed compounds could protect nerve cells from Alzheimer’s

As spring arrives in the northern hemisphere, many people are cursing ragweed, a primary culprit in seasonal allergies. But scientists might have discovered a promising new use for some substances produced by the pesky weed. In ACS’ Journal of Natural Products, researchers have identified and characterized ragweed compounds that could help nerve cells survive in the presence of Alzheimer’s disease […]

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Chemical modifiers tag-team to regulate essential mechanism of life: Basic science discovery explains a fundamental way human cells differ from yeast cells

Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription. A gene’s job is to provide a cell with the instructions to create a specific protein. The first step of this process is called transcription, during which the DNA is copied into RNA. The scribe is an enzyme called RNA […]

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How viruses outsmart their host cells: Scientists decipher protein structure after more than fifty years of research

Viruses depend on host cells for replication, but how does a virus induce its host to transcribe its own genetic information alongside that of the virus, thus producing daughter viruses? For decades, researchers have been studying a type of bacteriophage known as ‘lambda’ to try and find an answer to this question. Using high-resolution cryo-electron microscopy, a research group from […]

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Diabetes breakthrough: Why 420 million people with diabetes can look forward to

Kidney Failure, Blindness, Heart Attack, Stroke. The list of complications of Diabetes and could easily be extend. To 825 billion dollars to the world health organization estimates that the health costs incurred each year in connection with the disease. Therefore, researchers around the world for many years, feverishly on technologies to enable new approaches for therapies. A Team from the […]

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Fine-tuning cell death: New component of death machinery revealed

An important component of the microscopic machinery that drives cell death has been identified by Walter and Eliza Hall Institute scientists. Studying the ‘pro-death’ machinery that forces damaged, diseased or unwanted cells to die, the research team revealed a protein called VDAC2 was critical for the function of a key pro-death protein called Bax. The team also showed VDAC2 contributed […]

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Molecular mechanisms of an African folk medicine: Analysis of leaf extract reveals novel chemistry for therapeutic ion channel activation

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy. The herbal medicine, a leaf extract from the shrub Mallotus oppositifolius, has been used […]

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