On the way to fighting staph infections with the body’s immune system

Researchers have gained a greater understanding of the biology of staphylococcus skin infections in mice and how the mouse immune system mobilizes to fight them. A study appears this week in the Proceedings of the National Academy of Sciences. Community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) typically causes skin infections but can spread throughout the body to cause invasive infections such […]

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Chemical modifiers tag-team to regulate essential mechanism of life: Basic science discovery explains a fundamental way human cells differ from yeast cells

Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription. A gene’s job is to provide a cell with the instructions to create a specific protein. The first step of this process is called transcription, during which the DNA is copied into RNA. The scribe is an enzyme called RNA […]

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Structure of the molecular machine that links carbohydrate and lipid metabolism

A research team led by dr. Kenneth Verstraete in the Unit for Structural Biology at the VIB-UGent Center for Inflammation Research has unraveled the three-dimensional structure and molecular mechanism of ATP citrate lyase (ACLY). This is a central metabolic enzyme — a protein that accelerates chemical reactions — important for the production of fatty acids and cholesterol in the human […]

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