Human antibody reveals hidden vulnerability in influenza virus

The ever-changing “head” of an influenza virus protein has an unexpected Achilles heel, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The team discovered and characterized the structure of a naturally occurring human antibody that recognizes and disrupts a portion of the hemagglutinin (HA) protein that the virus […]

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Antibody therapy training phagocytes to destroy tumors now tested on patients

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse models, and the development of the therapy has now progressed to patient testing in a phase I/II clinical trial. One reason behind many unsuccessful […]

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