A possible blood test for detecting Alzheimer’s disease before symptoms show

A team of researchers from Australia, the U.K. and Sweden has found a possible method to test blood samples for Alzheimer’s disease before symptoms appear. In their paper published in the journal Science Advances, the group describes their testing system and its performance. As medical scientists continue to search for ways to prevent people from developing Alzheimer’s disease, they also […]

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Study Offers Hint of Hope for Staving Off Dementia in Some People

In dementia research, so many paths have led nowhere that any glimmer of optimism is noteworthy. So some experts are heralding the results of a large new study, which found that people with hypertension who received intensive treatment to lower their blood pressure were less likely than those receiving standard blood pressure treatment to develop minor memory and thinking problems […]

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Lifespan brain study adds possible clue in predicting Alzheimer’s

New research from The University of Texas at Dallas suggests that periodic evaluation of changing amyloid levels in certain brain structures may offer an important clue into who may be on a trajectory toward Alzheimer’s disease. Deposits of a protein called amyloid in the brain are one of the earliest signs that an individual is at high risk for developing […]

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Antiepileptic drugs linked to increased hospital stays in persons with Alzheimer’s disease

People with Alzheimer’s disease who used antiepileptic drugs had a higher number of accumulated hospital stays than people with Alzheimer’s disease who did not use antiepileptics, according to a new study from the University of Eastern Finland. The results were published in the Journal of American Medical Directors Association. During a two-year follow-up, persons who initiated antiepileptic drugs accumulated approximately […]

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A new hope in treating neurodegenerative disease

Alzheimer’s disease (AD) is the most representative degenerative brain disease, accounting for 60 to 80% of all dementia cases. In search for new mechanism for AD, the research team led by Professor Seong-Woon Yu of Brain and Cognitive Sciences paid attention to the autophagy of microglia, brain immune cells, is suppressed by inflammation. ‘Microglia’ are phagocytic immune cells which are […]

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Drug used to treat stroke may also prevent Alzheimer’s

Experimental stroke drug may also prevent Alzheimer’s by ‘preventing the build-up of toxic proteins in the brain’ Giving mice the medication 3K3A-APC stopped Alzheimer’s symptoms  3K3A-APC is used to reduce bleeding within the brain tissue of stroke patients Reduces inflammation, and protects nerve cells and the lining of blood vessels   e-mail View comments An experimental drug used to treat stroke […]

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Biologists identify promising drug for ALS treatment

A new drug could significantly slow the progression of ALS, also known as Lou Gehrig’s disease, according to new research by University of Alberta biologists. Current treatments slow progression of the degenerative disease by only a few months, and these findings could revolutionize the treatment of patients suffering from ALS, extending and improving quality of life. The drug, called telbivudine, […]

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Researchers classify Alzheimer’s patients in six subgroups

Researchers studying Alzheimer’s disease have created an approach to classify patients with Alzheimer’s disease, a finding that may open the door for personalized treatments. “Alzheimer’s, like breast cancer, is not one disease,” said lead author Shubhabrata Mukherjee, research assistant professor in general internal medicine at the University of Washington School of Medicine. “I think a good drug might fail in […]

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Microglia react distinctively during inflammation: LIH scientists provide new insights into function and heterogeneity of brain immune cells

The NorLux Neuro-Oncology Laboratory at LIH’s Department of Oncology conducts research on brain diseases, with a special emphasis on glioma biology, drug resistance and systems approaches. Within this research unit, Dr. Alessandro Michelucci focuses on the role of glial cells and inflammatory responses. Jointly with team member Dr. Carole Sousa and collaborating research groups from LIH and the University of […]

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A molecule for fighting muscular paralysis

Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva (UNIGE), Switzerland, — working in collaboration with the University of Strasbourg, France, — have identified a molecule that not only greatly reduces the progression of the […]

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