Pinpointing how cells regulate long-lasting memories

The brain has a knack for safekeeping our most treasured memories, from a first kiss to a child’s birth. In a new study in mouse cells, Columbia neuroscientists have mapped some of the molecular machinery that helps the brain maintain these kinds of long-term memories. By observing the activity of nerve cells of the brain, called neurons, that were extracted […]

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Gene linked to Alzheimer’s disease is involved in neuronal communication

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer’s disease susceptibility. Integrating experiments in fruit flies, mice and human brains, a multi-institutional team led by researchers at Baylor College of Medicine found that the CD2AP gene is involved in synaptic transmission, the process by which neurons communicate. Digging deeper, […]

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A Brain Scan May Predict Alzheimer’s. Should You Get One?

Juli Engel was delighted when a neurologist recommended a PET scan to determine whether amyloid — the protein clumps associated with an increased risk of Alzheimer’s disease — was accumulating in her mother’s brain. “My internal response was, ‘Yay!’” said Ms. Engel, 65, a geriatric care manager in Austin, Tex., who has been making almost monthly trips to help her […]

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Blood test is 94% accurate at identifying early Alzheimer’s disease

Up to two decades before people develop the characteristic memory loss and confusion of Alzheimer’s disease, damaging clumps of protein start to build up in their brains. Now, a blood test to detect such early brain changes has moved one step closer to clinical use. Researchers from Washington University School of Medicine in St. Louis report that they can measure […]

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Smart brain stimulators: Next-gen Parkinson’s disease therapy

Researchers at the University of Houston have found neuro biomarkers for Parkinson’s disease that can help create the next generation of “smart” deep brain stimulators, able to respond to specific needs of Parkinson’s disease patients. Those with the disease often undergo the high-frequency brain stimulation, a well-established therapy for the progressive nervous system disorder that affects movement, but the therapy […]

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Alzheimer’s protein is likely held together with many weak chemical interactions: Model reveals new role for overlooked electron relationships

The chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide a new way for researchers to understand proteins that cause disease and help them gain insights into the fundamentals of chemistry. Chemists at the University of Tokyo modeled the building blocks of the protein structure that causes Alzheimer’s disease, […]

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10 incredible health benefits of turmeric

If you’re using turmeric only for the occasional curry, you’re missing out. This wonder spice, made from the root of a plant in the ginger family, has amazing health benefits. These turmeric benefits will have you adding the spice to every dish you can. 10 PHOTOSHealth benefits of turmericSee GalleryHealth benefits of turmeric Decrease Inflammation The main reason people are […]

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Specific multinutrient combination benefits patients with early stage Alzheimer’s disease

A new longitudinal study has shown that a nutritional drink designated a “food for special medical purposes” containing the multinutrient combination Fortasyn Connect can benefit patients with the earliest stages of Alzheimer’s disease (AD), mild cognitive impairment, who are at risk of progressing to the dementia stage of AD, report scientists in the Journal of Alzheimer’s Disease Reports. The purpose […]

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Ragweed compounds could protect nerve cells from Alzheimer’s

As spring arrives in the northern hemisphere, many people are cursing ragweed, a primary culprit in seasonal allergies. But scientists might have discovered a promising new use for some substances produced by the pesky weed. In ACS’ Journal of Natural Products, researchers have identified and characterized ragweed compounds that could help nerve cells survive in the presence of Alzheimer’s disease […]

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Alzheimer’s disease is a ‘double-prion disorder’: Self-propagating amyloid and tau prions found in post-mortem brain samples, with highest levels in patients who died young

Two proteins central to the pathology of Alzheimer’s disease act as prions — misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape — according to new UC San Francisco research. Using novel laboratory tests, the researchers were able to detect and measure specific, self-propagating prion forms of the proteins amyloid […]

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