Research suggests expanding amblyopia treatment approaches

When University of California, Irvine neurobiologist Carey Y.L. Huh, Ph.D., set her sights on discovering more about amblyopia, she brought personal insight to her quest. As a child, Huh was diagnosed with the condition, which is often called “lazy eye.” Huh is a researcher in the lab of UCI associate professor of neurobiology & behavior Sunil Gandhi. She and her […]

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Black kids and suicide: Why are rates so high, and so ignored?

Teen suicide rates among black youth are increasing. In 2016 and again in 2018, national data revealed that among children age 5-11, black children had the highest rate of death by suicide. For the years 2008 to 2012, 59 black youth died by suicide, up from 54 in the years 2003-2007. Also, the 2015 Centers for Disease Control and Prevention’s […]

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New study identifies potential path forward for brachial plexus injury recovery

On average, an estimated three out of every 1,000 newborns will suffer a brachial plexus injury during birth, damaging the bundle of nerves that connect the brain and spinal cord to the shoulders, arms and hands. In the most traumatic cases, even with surgery and physical therapy as an infant, there is no treatment that can guarantee a full recovery. […]

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How decisions unfold in a zebrafish brain

Some things we do appear almost automatic, like opening the fridge when feeling hungry or flipping on the air conditioning when the temperature rises. Although such decisions don’t seem to take much thought, they are in fact generated by millions of neurons and numerous interactions among several brain regions—a dynamic system so complex that scientists aren’t able to observe it […]

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Body’s natural signal carriers can help melanoma spread

A new study from Finland sheds fresh light on how melanoma cells interact with other cells via extracellular vesicles they secrete. The researchers found that extracellular vesicles secreted by melanoma cells use the so-called hedgehog signaling pathway to intensify the malignant properties of the cells they are targeting. The discovery can help in the development of better treatment and diagnostics […]

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Chemicals between us: Surprising effects of oxytocin on cocaine addiction

A team of addiction researchers at the Medical University of South Carolina (MUSC) report in Psychopharmacology that oxytocin, a hormone produced naturally in the hypothalamus, has significant gender differences when used as a treatment for cocaine-addicted individuals with a history of childhood trauma. The MUSC team was led by Jane E. Joseph, Ph.D., a professor in the Department of Neuroscience, […]

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Researchers find strengths and gaps in Thailand diabetes care

As Thailand transitions to a high-middle-income country, noncommunicable chronic diseases such as diabetes are on the rise. A new study by researchers from Boston University School of Public Health (BUSPH) and Chulalongkorn and Mahidol Universities in Bangkok identifies the strengths and weaknesses of diabetes care in Thailand’s universal health system. Published in the journal PLOS ONE, the study found that […]

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Blood-clotting protein and blood platelets promote immune evasion, cancer progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer. The findings show how thrombin, a clotting protein in the blood, causes blood platelets to release transforming […]

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Cannabinoids improve symptoms in mice with endometriosis

Initial results from treating endometriosis in mice with cannabinoids suggest they can alleviate some symptoms of the disease, according to a new study in the open-access journal eLife. The findings have led to the start of a clinical trial in collaboration with the Gynecology Service of the Hospital Clinic of Barcelona, Spain. This trial will evaluate the possible benefits of […]

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Circular RNA limits skin cancer spread

A mysterious piece of genetic material restrains the spread of skin cancer cells, but is frequently lost as they mature, a new study finds. Published online January 13 in Cancer Cell, the new work revolves around circular RNA, a recently described type of ribonucleic acid (RNA). Typically, DNA blueprints are converted into RNA and then into proteins with cellular functions. […]

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